NYU Data Catalog

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  • NYU Dataset

    Chronic Stress Primes Innate Immune Responses in Mice and Humans

    Authors
    Tessa J. Barrett
    Emma M. Corr
    Coen van Solingen
    Florencia Schlamp
    18 more author(s)...
    Description

    Psychological stress (PS) is linked with systemic inflammation. It accelerates inflammatory disease progression and monocytes are key in sustaining systemic inflammation. However, the mechanisms underlying stress-mediated inflammation and future health risk remains unknown. This study examined the impact of psychological stress on monocytes. They showed that PS induces remodeling of the chromatin landscape...

    Subject
    Genomics
    Access Rights
    Free to All
  • NYU Dataset

    Adipose Tissue Macrophages Adapt to Inflammatory and Metabolic Challenges

    Authors
    Hernandez Moura Silva
    Andre Bafica
    Gabriela Flavia Rodrigues-Luiz
    Jingyi Chi
    13 more author(s)...
    Description

    Adipose tissue macrophages (ATMs) change during metabolic stress and are thought to contribute to metabolic syndrome. This study examined ATM subpopulations in steady state and in response to nutritional and infectious challenges. They characterized the epididymal white adipose tissue (eWAT) lymphoid and myeloid cell populations under steady state using RNA sequencing to analyze the transcriptome of...

    Subject
    Genomics
    Access Rights
    Free to All